Sermorelin is a synthetic 29-amino acid peptide representing the biologically active N-terminal fragment of endogenous GHRH (1-29). In laboratory and cellular models, research focuses on its selective activation of pituitary GHRH receptors to stimulate the natural, pulsatile release of growth hormone (GH) and subsequent downstream production of insulin-like growth factor 1 (IGF-1). Researchers study its role in endocrine signaling, cellular regeneration, and body composition regulation.
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